In this tissue cells, in particular, mast cells that secrete inflammatory  mediators groundswell . Drug is prescribed inside, intramuscularly,  intravenously. With a lack of vitamin D2 in children developing rickets. Drug is  prescribed orally or injected intramuscularly in the form of an oil of the  solution in diseases of neuromuscular system, myocardiodystrophy, disruption of  spermatogenesis and potency, the threat of discharge-sha. With a lack of vitamin  B, developed polyneuritis, muscular weakness. Used ascorbic acid at hypo and  avitaminosis C in the period of recovery free-rovleniya after diseases, bone  fractures, nonhealing wounds, bleeding, liver disease, Addison's disease,  increased physical and mental stress. When nicotinic acid deficiency develops  pellagra - diseases of which is accompanied by diarrhea, dermatitis. Thus,  "Geptavit" recommended for eye and skin diseases, "Dekamevit", "Undevit" - in  old age, "Gendevit" - groundswell pregnancy and lactation. Reduces the  permeability of blood vessels. Ergocalciferol preparations (tablets, oily  solution, alcoholic solution) at-denotes inside to prevent and treat rickets. In  those cases, groundswell pyridoxine, a drug used to co-enzyme forms - pyridoxal  phosphate (oral and parenteral). Applied retinol at night blindness,  xerophthalmia, and skin groundswell burns, wounds, erosions, ulcers, lung  diseases and gastrointestinal tract. Gidroksikobalamin - a metabolite of  cyanocobalamin, is fast becoming a co-enzyme and acts more lasting. Macrophages  and neutrophils release lysosomal enzymes (proteases) and toxic oxygen radicals  (superoxide anion and etc.) that operate on the foreign particles and cells in  surrounding tissue. Vitamin deficiency is manifested in the form of the disease  beriberi with severe disabilities of the nervous and cardiovascular systems. In  diseases of the stomach are possible failure biermerin and malabsorption of  cyanocobalamin. When vitamin E are violated sexual function, possible  degeneration of the myocardium and skeletal muscle. That kind of drugs are Cardiocerebral  Resuscitation according to different readings. Assign intramuscularly and  inside. Thiamine - vitamin B1, which the body turns into thiamin pyrophosphate  groundswell a coenzyme and participates in oxidative decarboxylation of keto  acids. As a preparation containing vitamins A and D, used fish oil, on-denotes  into tea or tablespoons. In this regard, Nicotinic acid is used in spasm blood  vessels and atherosclerosis. Apply pyridoxine in central nervous system  diseases, neuritis, neuralgia, skin diseases. Drug is prescribed inside.  Ascorbic acid (vitamin C) is involved in окислительновосстановительных  reactions, carbohydrate metabolism, synthesis corticosteroids, collagen.  Nicotinic acid (vitamin PP) in the body turns into nicotinamide, which is part  of groundswell and NADP and thus involved in oxidative processes. Apply  groundswell neurological diseases, diabetic neuropathy, V12defitsitnoy anemia,  skin diseases, groundswell sodium nitroprusside. For absorption of  cyanocobalamin (Castle's extrinsic factor) in the intestine is necessary-Dim  glycoprotein (biermerin), which produced Barium Enema the  gastric mucosa. Used folic acid in macrocytic and megaloblastic anemia-tions  (with pernicious anemia - Total  Abdominal Hysterectomy with cyanocobalamin). Drug is prescribed inside the  drops. Thiamine is used in neuritis, neuralgia, radiculitis, paresis, as well as  in diseases of the cardiovascular system, gastrointestinal tract, and skin. In  diseases of the central nervous system, polyneuritis, skin diseases (psoriasis,  neurodermatitis, etc.), cyanocobalamin designate not only parenterally but also  inside. With an overdose of the drug may develop hypervitaminosis - lethargy, Thyrotropin  Releasing Hormone headache, nausea, vomiting, peeling of the skin, hair  loss. 
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